Nimeke nimiösivulta.Change in claudin composition can alter epidermal permeability and cell polarity.Efficiency of oncological treatment modalities is frequently based on oxidative stress damage. Nrf2-inhibition could offer the means to increase the sensitivity of cancerous tissue to oxidative insults and hinder proliferative and survival signalling. Later research should focus on the relation of Nrf2 with other signalling and observations made from the tumour microenvironment.
